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Vladimir Lazar Selected Research

AVE1642

5/2013A dose finding, safety and pharmacokinetic study of AVE1642, an anti-insulin-like growth factor-1 receptor (IGF-1R/CD221) monoclonal antibody, administered as a single agent and in combination with docetaxel in patients with advanced solid tumours.

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Vladimir Lazar Research Topics

Disease

50Neoplasms (Cancer)
01/2022 - 08/2004
9Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 07/2007
7Breast Neoplasms (Breast Cancer)
11/2016 - 01/2009
6Melanoma (Melanoma, Malignant)
04/2013 - 04/2006
4Carcinogenesis
09/2011 - 07/2005
4Tetraploidy
07/2010 - 06/2006
3Glioma (Gliomas)
01/2012 - 01/2007
2Triple Negative Breast Neoplasms
11/2016 - 06/2014
2Neoplasm Metastasis (Metastasis)
11/2016 - 05/2015
2Lung Neoplasms (Lung Cancer)
09/2012 - 08/2012
2Genomic Instability
09/2011 - 07/2010
2Burkitt Lymphoma (Burkitt's Lymphoma)
09/2009 - 02/2005
2Infections
03/2004 - 10/2003
1Head and Neck Neoplasms (Head and Neck Cancer)
01/2019
1Pathologic Neovascularization
11/2016
1von Hippel-Lindau Disease (von Hippel Lindau Disease)
11/2014
1Hypoxia (Hypoxemia)
11/2014
1Colorectal Neoplasms (Colorectal Cancer)
07/2014
1Acute Promyelocytic Leukemia
10/2013
1Adenocarcinoma of Lung
09/2013
1Sarcoma (Soft Tissue Sarcoma)
05/2013
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
01/2013
1Diffuse Intrinsic Pontine Glioma
01/2012
1Brain Neoplasms (Brain Tumor)
01/2012
1Supratentorial Neoplasms
01/2012
1Starvation
12/2011
1Thrombocytopenia (Thrombopenia)
02/2011
1Leukemia
02/2011
1Ependymoma
09/2010

Drug/Important Bio-Agent (IBA)

12Proteins (Proteins, Gene)FDA Link
11/2016 - 10/2003
9DNA (Deoxyribonucleic Acid)IBA
09/2020 - 06/2006
9Biomarkers (Surrogate Marker)IBA
11/2016 - 05/2010
6MicroRNAs (MicroRNA)IBA
06/2015 - 03/2010
6Cisplatin (Platino)FDA LinkGeneric
09/2012 - 06/2006
4OligonucleotidesIBA
09/2009 - 07/2005
3Pharmaceutical PreparationsIBA
01/2019 - 04/2009
3ParaffinIBA
01/2019 - 09/2011
3RNA (Ribonucleic Acid)IBA
01/2019 - 03/2007
3Cadherins (E-Cadherin)IBA
07/2014 - 03/2007
3Biological ProductsIBA
09/2013 - 03/2012
2Axitinib (AG 013736)IBA
01/2022 - 04/2021
2Nucleic AcidsIBA
04/2020 - 01/2017
2Epidermal Growth Factor (EGF)IBA
11/2016 - 10/2009
2Messenger RNA (mRNA)IBA
09/2013 - 10/2008
2Transcription Factors (Transcription Factor)IBA
02/2011 - 03/2004
1avelumabIBA
01/2022
1pembrolizumabIBA
01/2022
1palbociclibIBA
01/2022
1EverolimusFDA Link
04/2021
1Fatty Acids (Saturated Fatty Acids)IBA
04/2020
1ProdrugsIBA
04/2020
1Lactic Acid (Lactate)FDA LinkGeneric
04/2020
1Glutamine (L-Glutamine)FDA Link
04/2020
1Natural Cytotoxicity Triggering Receptor 2IBA
01/2019
1Proliferating Cell Nuclear Antigen (PCNA)IBA
01/2019
1Natural Killer Cell ReceptorsIBA
01/2019
1Formaldehyde (Formol)FDA Link
01/2019
1LigandsIBA
01/2019
1ProgesteroneFDA LinkGeneric
11/2016
1Semaphorins (Semaphorin)IBA
11/2016
1Untranslated RNA (Noncoding RNA)IBA
11/2016
1Adrenergic Agents (Adrenergic Drugs)IBA
05/2015
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2015
1Bevacizumab (Avastin)FDA Link
04/2015
1CytokinesIBA
07/2014
1Checkpoint Kinase 1IBA
06/2014
1Dacarbazine (DIC)FDA LinkGeneric
04/2014
1Sorafenib (BAY 43-9006)FDA Link
04/2014
1Kazal Pancreatic Trypsin InhibitorIBA
12/2013
1ArsenicIBA
10/2013
1Tretinoin (Retinoic Acid)FDA LinkGeneric
10/2013
1sorbitan monolaurateIBA
10/2013
1Trastuzumab (Herceptin)FDA Link
10/2013
1Retinoic Acid Receptor alphaIBA
10/2013
1Cathepsin DIBA
09/2013
1AVE1642IBA
05/2013
1Small Interfering RNA (siRNA)IBA
04/2013
1CarcinogensIBA
09/2012
1CalreticulinIBA
09/2012
1Cadmium Chloride (Cadmium Dichloride)IBA
09/2012
1N-acetylsphingosineIBA
09/2012
1Cytotoxins (Cytolysins)IBA
08/2012
1Glutathione (Reduced Glutathione)IBA
08/2012
1Vitamin B 6IBA
08/2012
1InterferonsIBA
03/2012
1dipinacoline glutamateIBA
01/2012
1MyoD ProteinIBA
12/2011
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
09/2011
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
10/2010
1brivanibIBA
10/2010
1Indicators and Reagents (Reagents)IBA
10/2010
1hydrogen sulfite (bisulfite)IBA
09/2010

Therapy/Procedure

12Therapeutics
01/2022 - 01/2007
3Precision Medicine
01/2019 - 01/2011
3Drug Therapy (Chemotherapy)
09/2011 - 12/2007
2Immunotherapy
01/2021 - 07/2008
2Aftercare (After-Treatment)
01/2013 - 03/2007
1Cell- and Tissue-Based Therapy (Cell Therapy)
04/2020
1Intravenous Administration
01/2019
1Adjuvant Chemotherapy
09/2016